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. 2015 Jan 27;10:609–631. doi: 10.2147/IJN.S71198

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© 2015 Vasconcelos et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Comparison of anti-inflammatory efficacy of PLGA-PEG NPs, PLGA-PEG-peptide NPs, and Ocufen^® in the (A) treatment and (B) prevention of ocular inflammation induced by SA in the rabbit eye.

Notes: Values are expressed as mean ± SD; *P<0.05, **P<0.01, and ***P<0.001 significantly lower than the inflammatory effect induced by SA; ^$P<0.05, ^$$P<0.01, and ^$$$P<0.001 significantly lower than anti-inflammatory efficacy of Ocufen^®.

Abbreviations: HIV-Tat, human immunodeficiency virus transactivator; NPs, nanoparticles; PEG, polyethyleneglycol; PLGA, poly(lactic-co-glycolic acid); POD, peptide for ocular delivery; SA, sodium arachidonate; SD, standard deviation.