Table 1. Mutational status of all 13 human melanoma cell lines.
BRAF | NRAS | PTEN | REFERENCE | |
---|---|---|---|---|
MEWO | wt | wt | + | [74](NF1 mutant) |
VM47 | wt | wt | + (weak) | own sequence |
WM3060 | wt | 61K | + | [75] |
VM15 | wt | 61K | + (weak) | own sequence |
M24met | wt | 61R | + | own sequence |
WM3670 | G469E | 12D | + | [75] |
WM35 | V600E | wt | + | [65, 76] |
LOX | V600E | wt | + | [77] |
A375 | V600E | wt | + | [77] |
HT168-M1 | V600E | wt | - | own sequence |
A2058 | V600E | wt | - | [77] |
WM239 | V600E | wt | - | [65, 76] |
HT199 | V600E | wt | - | own sequence |