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| Items | N | Baseline | Week 48 | p |
|---|---|---|---|---|
| Intrahepatic HBV total DNA | 20 | 3.5×107 | 4.5×103 | < 0.01 |
| (Copies/106 cells, Median, range) | (4.8×106~6.7×108) | (7.2×102~6.1×104) | ||
| Intrahepatic HBV cccDNA | 20 | 1.3×106 | 3.6×103 | < 0.01 |
| (Copies/106 cells, Median, range) | (4.5×104~2.1×107) | (6.2×102~5.1×104) | ||
| Percentage of HBV cccDNA (%) | 20 | 3.4 (0.2–28.4) | 85.0 (43.1~96.2) | < 0.01 |
