Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Geometry of the charge relay system: Distances of salt bridges within the simulations of NLRP pyrin domains are monitored over simulation time. (A) Distance of R84 and D86, (B) Distance of E26 and R84 for six simulations. NLRP14-L84R and NLRP4 both stay in the closed starting conformation with two fully formed salt bridges. Four other systems stay in their extended conformation and do not form contacts within these three residues.
