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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Neurobiol Aging. 2014 Nov 15;36(2):1045–1056. doi: 10.1016/j.neurobiolaging.2014.11.007

Figure 2. Age reduces NPY+ cells and NPY protein in mouse OE.

Figure 2

(A–B) Representative images of NPY-immunoreactive cells in the OE of IP3R3+/− mice at 2 and 24 months. Scale bar = 20 µm. (C) The number of NPY+ cells is significantly reduced in the ectoturbinate 2 and endoturbinate II OE of IP3R3+/− mice at 24 vs. 2 months. * p < 0.05 (Student’s T test, n = 4 and 6 mice, respectively). (D) The NPY protein level is significantly reduced in the OE of IP3R3+/− mice at 24 months compared to 2 months. * p < 0.01 vs. 2, 6 and 12 months (one-way ANOVA followed by Newman-Keuls post-hoc test; n = 4 mice per group). (E) The NPY mRNA levels in the OE of IP3R3+/− mice are comparable among all ages checked. p > 0.05 (one-way ANOVA followed by Newman-Keuls post-hoc test; n = 4 mice per group).