Table 1.

Characteristics in 1991/1993 of Participants Excluded and Included in the Analyses and Mean Long-term Levels of Interleukin-6 Assessed in 1997/1999 and 2002/2004 of Those Included

Variables	Category	N or Mean (SD)∗	Mean Long-term IL-6 (95% CI) (pg/mL) or ρ†	P Value‡
Sex	Men	3334	1.65 (1.62-1.68)	.05
	Women	1266	1.59 (1.55-1.64)
Age	Per year	49.6 (6.1)	0.25	<.001
Ethnicity	White	4317	1.61 (1.59-1.64)	<.001
	South Asian	185	2.07 (1.92-2.23)
	Black	98	1.63 (1.47-1.81)
Socioeconomic status	Low	542	1.78 (1.70-1.86)	<.001
	Intermediate	2046	1.68 (1.64-1.72)
	High	2012	1.55 (1.52-1.59)
Living alone	No	3588	1.61 (1.58-1.63)	.001
	Yes	1012	1.72 (1.67-1.78)
Smoking habits	Nonsmokers	2402	1.55 (1.52-1.59)	<.001
	Former smokers	1657	1.64 (1.60-1.68)
	Current smokers	541	1.98 (1.90-2.07)
Total energy intake	Per kcal/d	2124	−0.05	.002
Physical activity	Inactive	808	1.76 (1.70-1.83)	<.001
	Moderately active	1313	1.62 (1.57-1.67)
	Active	2479	1.60 (1.57-1.63)
General health questionnaire depression cases	No	4040	1.63 (1.61-1.66)	.99
	Yes	560	1.63 (1.5-1.70)
Coronary heart diseases	No	4487	1.63 (1.60-1.65)	.01
	Yes	113	1.84 (1.67-2.02)
Body mass index	per kg/m²	25.0	0.32	<.001
Hypertension	No	3803	1.58 (1.55-1.60)	<.001
	Yes	797	1.92 (1.86-2.00)
Diabetes	No	4487	1.63 (1.60-1.65)	.05
	Yes	113	1.79 (1.63-1.98)
HDL-cholesterol	per mmol/L	1.43 (0.40)	−0.18	<.001
Use of anti-inflammatory drugs	No	3939	1.59 (1.57-1.62)	<.001
	Yes	661	1.90 (1.83-1.97)

CI = confidence interval; HDL = high-density lipoprotein; IL = interleukin; SD = standard deviation.

^∗N presented for categoric variables and mean (SD) for continuous variables.

^†IL-6 geometric means with its 95% CI (pg/mL) shown for categoric variables and Spearman correlation coefficient for continuous variables.

^‡P value for association with chronic IL-6.