Table 6.

Six-Minute-Walk Test before and after Treatment with Sirolimus in 25 Patients with Lymphangioleiomyomatosis

	Before Sirolimus Began	After Sirolimus Began	P Value
Mean time, yr	−0.5 ± 0.4	3.4 ± 1.9
Distance, m	373 ± 109	412 ± 85	0.164
Initial heart rate, beats/min	90 ± 12	88 ± 12	0.551
Final heart rate, beats/min	115 ± 17	122 ± 15	0.129
Initial SaO2, %	97 ± 2	99 ± 1	<0.001
Final SaO2, %	87 ± 7	89 ± 5	0.251
Oxygen, L/min	3.5 ± 3.5	4.2 ± 2.8	0.430