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. 2014 Dec 12;4(12):e269. doi: 10.1038/bcj.2014.89

Figure 1.

Figure 1

Transplantation of BCR-ABL1-transduced CB cells to NSG mice induces a lethal disorder. (a) Flowchart showing generation of BCR-ABL1 transduction model and analysis of transplanted NSG mice. (b) Measurements of white blood cells (WBCs), red blood cells (RBCs) and platelets (Plts) in peripheral blood in transplanted mice at 4, 8 and 12 weeks after transplantation. (c) Survival of all transplanted mice. (d) Spleen weights of mice that succumbed to the disease. (e) Gene expression analysis of BCR-ABL1 in sorted GFP− BM cells from BA mice. Sorted BCR-ABL1+ GFP+ cells were used as a positive control.