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Effect of the pan-cytochrome P450 (CYP) inhibitor or CYP2B inhibitor, 1-aminobenzotriazole (ABT) or miconazole, on EFV-induced cell injury. Hepatocytes were exposed to EFV (50 µM) in the presence or absence of ABT or miconazole, and LDH release was determined after 24 h. Data are mean±SD of three independent hepatocyte preparations using quadruplicate wells. *P<0.05 versus solvent control.
