Skip to main content
. 2015 Jan 16;4:279–288. doi: 10.1016/j.redox.2015.01.005

Fig. 3.

Fig. 3

Time course of EFV-induced superoxide anion and peroxynitrite generation in hepatocytes. Hepatocytes were preloaded with MitoSOX red or CBA and exposed to EFV (30 or 50 µM). (A) MitoSOX Red-derived fluorescence, indicative of increased superoxide generation. (B) Hydroxycoumarin fluorescence generated from peroxynitrite-mediated CBA oxidation was serially recorded with a plate reader. Data are mean±SD of three independent hepatocyte preparations using quadruplicate wells. *P<0.05 versus solvent control.