Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan 16;4:279–288. doi: 10.1016/j.redox.2015.01.005

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 6 — Inhibitory effects of ferroporphyrins on CYP3A4 and CYP2B6 activity. Baculosomes expressing the recombinant human CYP isoforms were incubated with Fe-TCP (A) or Fe-TMPyP (B) and the fluorogenic substrate, BOMCC (10 µM). The rates of formation of the fluorescent reaction product, 3-cyano-7-hydroxycoumarin, was determined (λ_ex 415/λ_em 460 nm). Data points are mean±SD of triplicate determinations (SDs are smaller than the symbols). Fe-TCP or Fe-TMPyP did not significantly interfere with the assay readouts.