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Effect of LPS pretreatment on the lethality and DNA fragmentation induced by LPS/D-GalN in TNFR2-/- mice.
| LPS pretreatment (0.1 mg) before challenge (h) |
Challenge: LPS (0.05 mg) + D-GalN (20 mg) |
|
| Lethality (dead/total) | DNA fragmentation | |
| None | 5/5 | + |
| 24 | 0/5 | - |
| 18 | 0/5 | - |
| 3 | 0/5 | - |
| 1.25 | 0/5 | - |
+, fragmentation present; -, fragmentation absent.
