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. 2005 Jun 28;11(24):3710–3713. doi: 10.3748/wjg.v11.i24.3710

Figure 3.

Figure 3

Light microscopic distributions of immunohistochemically stained CAV-1 and -2 in PBC stage 3 liver tissue. A: CAV-1, ×100; B: CAV-2, ×100; C: double staining of CAV-1 and cytokeratin 7, ×100; D: double staining of CAV-2 and cytokeratin 7, ×100. Hematoxylin counterstain. Reaction products showing CAV-1 and -2 are localized abundantly on hepatic sinusoidal lining cells and proliferative bile ductules. Regenerating bile ductules at the interface of portal tracts and necrotic areas are immunostained intensely for CAV-1 and -2, showing significant increase compared to control liver. Arrow denotes proliferative bile ductule.