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The interaction effect of the UGT1A7*3 allele and variant-211 UGT1A1 allele upon the development of CRC.
| UGT1A7*3/ variant-211UGT1A1 |
Number (%) |
OR (95%CI) | P | |
| Cases (n = 268) | Controls (n = 441) | |||
| Absent/absent | 145 (54.1) | 302 (68.5) | 1.00 | |
| Present/absent | 28 (10.4) | 45 (10.2) | 1.30 (0.78-2.16) | 0.39 |
| Absent/present | 13 (4.8) | 21 (4.8) | 1.29 (0.63-2.65) | 0.33 |
| Present/present | 82 (30.6) | 73 (16.5) | 2.34 (1.61-3.40) | <0.001 |
| Expected by additive1 | 1.59 | |||
Expected OR under no-interaction additive model.
