Table 4.
Clinicopathological feature |
KRAS |
BRAF |
||
Mutant/tested cases | P value | Mutant/tested cases | P value | |
Gender | ||||
Male | 100/277 (36.1) | 0.336 | 7/254 (2.8) | 0.048 |
Female | 84/208 (40.4) | 13/196 (6.6) | ||
Age (yr) | ||||
< 50 | 11/50 (22) | 0.014 | 3/47 (6.4) | 0.758 |
≥ 50 | 173/435 (39.8) | 17/403 (4.2) | ||
Location | ||||
Right colon | 67/161 (41.6) | 0.318 | 14/146 (9.6) | 0.001 |
Left colon | 50/150 (33.3) | 3/167 (2.1) | ||
Rectum | 68/177 (38.4) | 3/140 (1.8) | ||
Mucin production | ||||
With | 41/108 (38) | 0.990 | 10/102 (9.8) | 0.006 |
Without | 144/380 (37.9) | 10/351 (2.8) | ||
Tumor differentiation | ||||
Poor | 25/84 (29.8) | 0.091 | 7/74 (9.5) | 0.045 |
Well-moderate | 160/404 (39.6) | 13/379 (3.4) | ||
Tumor stage | ||||
I-II | 85/232 (36.6) | 0.553 | 10/218 (4.6) | 0.918 |
III-IV | 97/247 (39.3) | 10/228 (4.4) |