Table 6.
Correlations between DNA mismatch repair protein expression deficiency and KRAS or BRAF status n (%)
| MMR status |
KRAS (n = 432) |
BRAF (n = 424) |
||
| Mutant/tested cases | P value | Mutant/tested cases | P value | |
| dMMR | 9/48 (18.8) | 0.0021 | 4/43 (9.3) | 0.264 |
| MLH1/PMS2 deficiency | 3/29 (10.3) | 0.0012 | 4/26 (15.4) | 0.0373 |
| MSH2/MSH6 deficiency | 6/19 (31.6) | 0.3833 | 0/17 (0) | 0.8173 |
| pMMR | 160/384 (41.7) | 16/381 (4.2) | ||
1
dMMR vs pMMR;
2
MLH1/PMS2 deficiency vs pMMR;
3
MSH2/MSH6 vs pMMR. MMR: DNA mismatch repair.