Table 3. Univariate Cox regression Analysis for Disease-free Survival and Overall Survival in Patients with Non-Small Cell Lung Cancer.
| Disease-free survival | Overall survival | |||
|---|---|---|---|---|
| HR (95%CI) | P value | HR (95%CI) | P value | |
| Age (years) | 1.012 (0.993–1.030) | 0.217 | 1.013 (0.994–1.032) | 0.193 |
| Gender | 0.860 | 0.925 | ||
| Male | 1.000 | 1.000 | ||
| Female | 0.961 (0.618–1.495) | 0.925 (0.595–1.439) | ||
| Tumor Laterality | 0.995 | 0.824 | ||
| Left | 1.000 | 1.000 | ||
| Right | 1.001 (0.675–1.485) | 1.046 (0.705–1.551) | ||
| Histology | 0.521 | 0.481 | ||
| Adenocarcinoma | 1.000 | 1.000 | ||
| SCC | 1.134 (0.773–1.663) | 1.148 (0.783–1.684) | ||
| Pleural Invasion | 0.104 | 0.110 | ||
| Absent | 1.000 | 1.000 | ||
| Present | 1.458 (0.926–2.297) | 1.448 (0.919–2.282) | ||
| Tumor Differentiation | 0.430 | 0.328 | ||
| Grade 1 | 1.000 | 1.000 | ||
| Grade 2 | 0.884 (0.397–1.796) | 0.791 (0.372–1.683) | ||
| Grade 3 | 1.098 (0.523–2.305) | 1.069 (0.509–2.243) | ||
| pTNM Status | <0.001 | <0.001 | ||
| Stage I | 1.000 | 1.000 | ||
| Stage II | 3.145 (1.890–5.232) | 2.982 (1.795–4.955) | ||
| Stage III | 3.647 (2.172–6.123) | 3.387 (2.020–5.679) | ||
| Adjuvant Chemotherapy | 0.006 | 0.017 | ||
| Yes | 1.000 | 1.000 | ||
| No | 1.762 (1.178–2.634) | 1.629 (1.092–2.430) | ||
| Cystatin SN Expression | <0.001 | 0.001 | ||
| Low | 1.000 | 1.000 | ||
| High | 2.099 (1.412–3.121) | 1.906 (1.284–2.830) | ||
Abbreviation: HR, hazard ratio; 95%CI, 95% confidence interval; SCC, squamous cell carcinoma; pTNM status, pathological Tumor-Node-Metastasis.