[Table/Fig-1]:

Changes in blood pressure

Measurement	Day 0	Day 60	Day 90	Day 150	p-value
Pulse rate(beats/min)	130±2.10	123±3.95	105±2.76	84.17±4.49	<0.001
Systolic blood pressure (mm Hg)	159±5.06	147.33±3.27	137.67±8.14	104.67±51.42	0.012
Diastolic blood pressure (mm Hg)	93.5±2.35	88.67±1.63	78.33±6.86	75.33±4.13	<0.001
Pulse pressure (mm Hg)	65.5±3.93	58.67±3.50	58±8.29	49.67±2.66	<0.001
Mean arterial blood pressure (mm Hg)	115±2.97	108±1.67	97.67±6.59	91.83±4.02	<0.001