Figure 5.

Target muscle reinnervation in mice after sciatic nerve crush injury.

Light micrographs following hematoxylin-eosin staining, obtained at 21 days after surgery, showing the target gastrocnemius muscle (A) at the contralateral, normal side (a) and the crushed side of animals receiving injection of saline (b), 2.5 mg/kg (c), 5.0 mg/kg (d), 10.0 mg/kg (e) of ABPPk, and 16.0 mg/kg of ABPP (f). Scale bar: 20 μm. Bar graph (B) comparing the cross sectional area value of gastrocnemius muscle fibers at the normal side and at the crushed side of mice receiving different treatments as indicated. All data are presented as the mean ± SD (n = 10). *P < 0.05, vs. saline treatment; #P < 0.05, vs. normal side (one-way analysis of variance plus Scheffé post hoc test); ABPP: Achyranthes bidentata polypeptides.