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Pharmacokinetic parameters of VEGF 121 and VEGF PADS
| Free VEGF | VEGF PADS | |||
|---|---|---|---|---|
| Central compartment volume of distribution | V c | (L) | 0.013 ± 0.005 | 0.013 ± 0.003 |
| Plasma clearance | Cl | (L min-1) | 0.0008 ± 0.0003 | 0.0004 ± 0.0004 |
| Area under curve | AUC | (nmol min L-1) | 3,863.8 ± 1,444.6 | 5,059.0 ± 528.5 |
| Distribution half life | t 1/2 dist | (min) | 8.6 | 7.2 |
| Terminal half life | t 1/2 term | (min) | 30.2 | 52.4 |
