Table 2.
Candidate Caenorhabditis briggsae-Specific GLD-1-Associated mRNAs
| WormBase Gene No. | Gene Name | Gene Product Notes | Total GBM Score |
|---|---|---|---|
| WBGene0028332 | CBG05982 | Small subunit of serine palmitoyltransferase | 0.912 |
| WBGene00033808 | CBG12955 | Domain of unknown function DUF148 | 1.677 |
| WBGene00032844 | Cbr-his-72 | Histone H3 | 0.963 |
| WBGene00038583 | Cbr-rbx-1 | RBX ring finger | NA |
| WBGene00032440 | Cbr-asp-5 | Aspartyl protease | −0.003 |
| WBGene00024012 | Cbr-dod-23 | Downstream of DAF-16 | 0.743 |
| WBGene00026551 | Cbr-skr-1 | Skp1-related ubiquitin ligase component | 0.332 |
| WBGene00031134 | Cbr-lys-2 | Lysozyme | NA |
| WBGene00035116 | CBG14697 | Proteolipid membrane potential modulator | 1.175 |
| WBGene00033455 | Cbr-ran-4 | RAN-associated nuclear transport factor 2 | NA |
| WBGene00036658 | Cbr-vha-3 | Vacuolar H+ ATPase, proteolipid subunit | NA |
| WBGene00027222 | Cbr-pes-9 | Peptidase M20 | 1.919 |
| WBGene00032414 | CBG11273 | 2.331 | |
| WBGene00025463 | Cbr-daz-1 | RRM RBP | 0.084 |
| WBGene00038288 | CBG18998 | Serine/threonine PP2A reg. subunit B″, subunit β | 1.198 |
| WBGene00026678 | Cbr-nlp-40 | Neuropeptide-like | 1.178 |
| WBGene00027603 | Cbr-lmp-1 | Lysosome-associated membrane glycoprotein | 0.561 |
| WBGene000034566 | Cbr-mdf-2 | HORMA DNA-binding domain, spindle checkpoint | NA |
| WBGene00026341 | Cbr-fat-4 | Fatty acid desaturase | NA |
| WBGene00034027 | Cbr-elb-1 | Elongin B, chromosome condensation factor | 1.895 |
| WBGene00028676 | Cbr-puf-7 | PUF RBP | NA |
| WBGene00027257 | Cbr-pas-1 | Proteasome α subunit | 2.566 |
| WBGene00025925 | CBG02968 | NA | |
| WBGene00031204 | CBG09646 | Enhancer of rudimentary | 1.436 |
| WBGene00025990 | Cbr-taf-13 | TBP-associated transcription factor family | NA |
| WBGene00024807 | CBG01590 | Centromere protein X | NA |
| WBGene00026127 | Cbr-tomm-40 | Translocase of outer mitochondrial membrane | NA |
| WBGene00042785 | Cbr-nos-2 | Nanos RBP | NA |
| WBGene00031008 | Cbr-cni-1 | Cornichon domain | NA |
| WBGene00026004 | Cbr-ebp-2 | RP/EB microtubule end-binding protein | NA |
| WBGene00028195 | Cbr-elo-3 | GNS1/SUR4 fatty acid elongation factor | NA |
| WBGene00041780 | CBG23419 | Translation elongation factor EF1 α | 1.184 |
| WBGene00027913 | Cbr-blos-2 | Biogenesis of lysosome-related organelles complex-1, subunit 2 | NA |
| WBGene00041670 | Cbr-ape-1 | Ankyrin repeats, apoptosis enhancer | 0.153 |
| WBGene00025363 | CBG02285 | Leucine-rich repeat | NA |
| WBGene00026898 | Cbr-dnc-6 | Dynactin complex subunit 6 | 0.085 |
| WBGene00033866 | Cbr-lir-1 | LIN-26-related | 2.800 |
| WBGene00037251 | CBG17687 | Peptidase M20 | 0.459 |
| WBGene00026895 | CBG04168 | DOMON domain | 0.782 |
| WBGene00039610 | Cbr-csc-1 | Chromosome segregation and cytokinesis factor | NA |
| WBGene00033472 | CBG12532 | Myb DNA-binding domain, associated with splicing | NA |
Note.—Only genes whose C. elegans homolog is expressed abundantly are included (see main text for discussion). GBM scores are totals from GBM_finder motifs in the 100 bp upstream or 250 bp downstream of the annotated start and stop codons of each gene model in WormBase. Positive values predict association with GLD-1, negative values nonassociation. NA, no motifs found.