Table 1.
Regional BPND# | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Subject | Sex | Age | Weight (kg) |
Injected Activity (MBq) |
MTL* | Hp | Am | pHp | IC | aCG | pCG | RN* | PC | OfC | TC | OC | FC |
1 | F | 27 | 89 | 204 | 2.59 | 2.08 | 1.14 | 1.74 | 1.61 | 1.08 | 0.86 | 0.94 | 0.73 | 1.08 | 1.27 | 0.63 | 0.77 |
2 | F | 27 | 79 | 192 | 2.23 | 1.67 | 1.12 | 1.65 | 1.53 | 1.07 | 0.73 | 0.72 | 0.95 | 0.88 | 1.39 | 0.75 | 0.99 |
3 | M | 32 | 113 | 200 | 3.15 | 2.65 | 2.08 | 2.24 | 2.19 | 1.83 | 1.54 | 1.56 | 0.80 | 1.68 | 1.31 | 0.79 | 0.81 |
4 | M | 22 | 97 | 204 | 1.86 | 1.14 | 0.52 | 1.27 | 1.27 | 0.71 | 0.51 | 0.37 | 0.87 | 0.85 | 1.27 | 0.64 | 0.79 |
5 | F | 38 | 114 | 196 | 2.63 | 1.85 | 1.03 | 1.80 | 1.40 | 1.13 | 0.85 | 0.80 | 0.72 | 1.02 | 1.20 | 0.66 | 0.73 |
6 | F | 38 | 58 | 196 | 2.07 | 1.11 | 0.72 | 1.10 | 1.52 | 1.50 | 0.87 | 0.59 | 1.27 | 1.31 | 1.51 | 0.89 | 1.37 |
Mean (S.D.) | 2.42 (0.46) | 1.75 (0.59) | 1.10 (0.54) | 1.63 (0.41) | 1.59 (0.32) | 1.22 (0.39) | 0.89 (0.34) | 0.83 (0.41) | 0.89 (0.20) | 1.14 (0.31) | 1.32 (0.11) | 0.73 (0.10) | 0.91 (0.24) | ||||
Test-Retest Variability (TRV) | 5.89 | 3.69 | 11.55 | 5.42 | 11.04 | 8.94 | 10.01 | 11.35 | 10.06 | 8.16 | 5.61 | 4.10 | 9.04 | ||||
Intra-Class Correlation (ICC) | 0.94 | 0.99 | 0.99 | 0.95 | 0.88 | 0.98 | 0.98 | 0.97 | 0.60 | 0.96 | 0.43 | 0.88 | 0.71 |
Denotes PET defined regions
BPND values calculated with MRTM.
Regions included are focal areas of uptake in the mesial temporal lobe (MTL; hand drawn), hippocampus (Hp), amygdala (Am), parahippocampal gyrus (pHp), insular cortex (IC), anterior cingulate gyrus (aCG), posterior cingulate gyrus (pCG), parietal cortex (PC) orbitofrontal cortex (OfC), temporal cortex (TC), occipital cortex (OC), frontal cortex (FC), and raphe nuclei (RN; PET defined).