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. Author manuscript; available in PMC: 2015 Feb 4.
Published in final edited form as: J Nucl Med. 2014 Nov 13;55(12):1973–1979. doi: 10.2967/jnumed.114.145151

Table 1.

Scan details and regional 18F-mefway BPND values with test-retest analysis

Regional BPND#
Subject Sex Age Weight
(kg)
Injected
Activity
(MBq)
MTL* Hp Am pHp IC aCG pCG RN* PC OfC TC OC FC
1 F 27 89 204 2.59 2.08 1.14 1.74 1.61 1.08 0.86 0.94 0.73 1.08 1.27 0.63 0.77
2 F 27 79 192 2.23 1.67 1.12 1.65 1.53 1.07 0.73 0.72 0.95 0.88 1.39 0.75 0.99
3 M 32 113 200 3.15 2.65 2.08 2.24 2.19 1.83 1.54 1.56 0.80 1.68 1.31 0.79 0.81
4 M 22 97 204 1.86 1.14 0.52 1.27 1.27 0.71 0.51 0.37 0.87 0.85 1.27 0.64 0.79
5 F 38 114 196 2.63 1.85 1.03 1.80 1.40 1.13 0.85 0.80 0.72 1.02 1.20 0.66 0.73
6 F 38 58 196 2.07 1.11 0.72 1.10 1.52 1.50 0.87 0.59 1.27 1.31 1.51 0.89 1.37
Mean (S.D.) 2.42 (0.46) 1.75 (0.59) 1.10 (0.54) 1.63 (0.41) 1.59 (0.32) 1.22 (0.39) 0.89 (0.34) 0.83 (0.41) 0.89 (0.20) 1.14 (0.31) 1.32 (0.11) 0.73 (0.10) 0.91 (0.24)
Test-Retest Variability (TRV) 5.89 3.69 11.55 5.42 11.04 8.94 10.01 11.35 10.06 8.16 5.61 4.10 9.04
Intra-Class Correlation (ICC) 0.94 0.99 0.99 0.95 0.88 0.98 0.98 0.97 0.60 0.96 0.43 0.88 0.71
*

Denotes PET defined regions

#

BPND values calculated with MRTM.

Regions included are focal areas of uptake in the mesial temporal lobe (MTL; hand drawn), hippocampus (Hp), amygdala (Am), parahippocampal gyrus (pHp), insular cortex (IC), anterior cingulate gyrus (aCG), posterior cingulate gyrus (pCG), parietal cortex (PC) orbitofrontal cortex (OfC), temporal cortex (TC), occipital cortex (OC), frontal cortex (FC), and raphe nuclei (RN; PET defined).