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. Author manuscript; available in PMC: 2015 Feb 4.
Published in final edited form as: J Pharm Sci Pharmacol. 2014 Jun 1;1(2):87–100. doi: 10.1166/jpsp.2014.1013

Figure 5.

Figure 5

Histone deacetylase (HDAC) inhibitors Trichostatin A (TSA) and Valproic acid (VPA) increases caspase 3/7 activity. Ewing Sarcoma (5838) cells were treated with variable amounts of VPA (0.1 mM, 1 mM and 3 mM)/TSA (0.02 μM, 0.2 μM and 2 μM) and DMSO as control for 24 hours. Caspase 3/7 activities were measured using Caspase-Glo 3/7assay reagent. Results shown are the mean of percentage of control in three independent experiments with standard deviation. **p < 0 01 compared with untreated controls.