Table 1.
Antimicrobial susceptibility of Neisseria gonorrhoeae isolates (n=193) from Belarus, 2010–2013
| Antimicrobial | MIC 50 / | Susceptible (%) | Intermediate susceptible (%) | Resistant (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MIC 90 / | 2010-2011 | 2012 | 2013 | 2010-2011 | 2012 | 2013 | 2010-2011 | 2012 | 2013 | |
| MIC range | (n=78) a | (n=75) | (n=40) | (n=78) a | (n=75) | (n=40) | (n=78) a | (n=75) | (n=40) | |
| (mg/L) | ||||||||||
| Penicillin Gb | 0.032/1/ | - | 88 | 78 | - | 5 | 10 | - | 7 | 13 |
| 0.008-2 | ||||||||||
| Ceftriaxoneb | 0.008/0.047/ | 100 | 100 | 100 | NA | NA | NA | 0 | 0 | 0 |
| <0.002-0.125 | ||||||||||
| Cefiximeb | 0.023/0.047/ | 100 | 100 | 97.5 | NA | NA | NA | 0 | 0 | 2.5 |
| <0.016-0.25 | ||||||||||
| Azithromycinb | 0.19/0.38/ | 65 | 83.3 | 90 | 23 | 15.3 | 10 | 12 | 1.3 | 0 |
| 0.032-1 | ||||||||||
| Ciprofloxacinb | 0.006/6/ | 64 | 79 | 72 | 1 | 0 | 0 | 35 | 21 | 28 |
| 0.003- >32 | ||||||||||
| Tetracyclineb | 0.38/24/ | 56 | 56 | 55 | 8 | 9 | 5 | 36 | 35 | 40 |
| 0.094-24 | ||||||||||
| Spectinomycinb | 12/16/3-16 | 100 | 100 | 100 | NA | NA | NA | 0 | 0 | 0 |
| Gentamicinc | 2010-2011: | 2012: | 2013: | |||||||
| MIC range: 0.25-16 mg/L; MIC50: 2 mg/L; MIC90: 4 mg/L | MIC range: 2-16 mg/L; MIC50: 4 mg/L; MIC90: 8 mg/L | MIC range: 3-12 mg/L; MIC50: 6 mg/L; MIC90: 8 mg/L | ||||||||
MIC50, minimum inhibitory concentration of 50% of isolates; MIC90, minimum inhibitory concentration of 90% of isolates; −, Not tested; NA, not applicable.
aDue to the few isolates obtained in 2011, isolates from 2010 (n=72) and 2011 (n=6) were evaluated as one time point.
bBreakpoints for susceptible and resistant isolates were according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST; www.eucast.org/clinical_breakpoints).
cBreakpoints not stated by any organization.