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Transmission electron microscopy of Hep-2 cells preparations infected with strain D92/09, where a profound cytotoxic effect both in parasitized (A) and in bacteria free cells (B and C) are observed. In bacteria infected cell, an almost complete destruction leading to nuclear damage is seen (A). In bacteria free cells cytotoxic effect manifested by membrane vesicles (B) and large cytoplasm vacuoles formation (C).
