Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Feb 4;9:22. doi: 10.3389/fncel.2015.00022

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Machado, Morte, Carreira, Azevedo, Takano, Iwata, Saido, Asmussen, Horwitz, Carvalho and Araújo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Calpastatin deficiency decreases DCX immunoreactivity and migration distance of newborn cells in the DG. Representative images from hippocampal brain sections of Cast^+/+ (A) and (E) and Cast^−/− (B) and (F) mice, showing migrating neuroblasts in red, labeled for DCX, and BrdU-positive cells in green. Percentage of DCX immunoreactivity in the DG (C). Distance migrated from the SGZ by the BrdU-positive/DCX-positive cells present in the GZ (D). Co-localization of BrdU and DCX is shown in the right panels of (E) and (F). Scale bars: 100 μm for (A) and (B); 20 μm for (E) and (F). Means ± SEM of at least 3 independent experiments. Two-tailed t-test, **p < 0.01 and ***p < 0.001 (significantly different from Cast^+/+).