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Therapeutic agents that are either FDA-approved or currently in clinical trials targeting the genetic aberrations found in HNSCC determined by Seiwert and colleagues (1). Red: oncogenes, Black: tumor suppressors, Blue box: HPV(−) tumors, Green box: HPV(+) tumors. The incidence of mutations (M) and amplifications (A) are separated by HPV status. Adapted from Seiwert et al. (1).
