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. Author manuscript; available in PMC: 2015 Feb 4.
Published in final edited form as: Wiley Interdiscip Rev Syst Biol Med. 2012 Mar 8;4(4):327–337. doi: 10.1002/wsbm.1169

Figure 4. plasma protein signatures of lung cancer derived from analysis of mouse models of cancer.

Figure 4

The heat map displays clustering together of lung cancer mouse models’ plasma proteome data. Below is a comparison between human lung adenocarcinoma plasmas and human lung non-adenocarcinoma plasmas of levels of proteins associated with an NKX2.1 signature identified in lung adenocarcinoma. An EGFR related protein network identified in plasma from an EGFR mutant lung cancer mouse model is shown. A list of proteins associated with a neuroendocrine signature in small cell lung cancer plasma is presented numbers refer to plasma protein case/control ratios and corresponding gene expression ratios in tumor tissue from the SCLC mouse model compared to controls.