Table 3.
Sensitivity index (SI) for each model parameter at different combinations of treatment and vaccination coverages. Higher values indicate that a parameter contributes a greater amount to the uncertainty in Re.
| 30% Vaccinated | 35% Vaccinated | 51% Vaccinated | 60% Vaccinated | |||
|---|---|---|---|---|---|---|
| Parameter | SI | SI | SI | SI | ||
| 30% treated | Secondary attack rate | θ | 0.966 | 0.966 | 0.961 | 0.955 |
| Antiviral treatment efficacy | εT | 0.025 | 0.025 | 0.025 | 0.024 | |
| Vaccine efficacy | εV | 0.001 | 0.002 | 0.006 | 0.012 | |
| Contact rate | c | 0.001 | 0.001 | 0.001 | 0.001 | |
| 1/(Duration of infectious period) | δ | <0.001 | 0.001 | <0.001 | <0.001 | |
| Proportion of infected individuals hospitalized | pH | <0.001 | 0.001 | <0.001 | <0.001 | |
| 37% treated | Secondary attack rate | θ | 0.946 | 0.945 | 0.941 | 0.935 |
| Antiviral treatment efficacy | εT | 0.043 | 0.043 | 0.043 | 0.042 | |
| Vaccine efficacy | εV | 0.001 | 0.002 | 0.006 | 0.012 | |
| Contact rate | c | 0.001 | 0.001 | 0.001 | 0.001 | |
| 1/(Duration of infectious period) | δ | <0.001 | 0.001 | <0.001 | <0.001 | |
| Proportion of infected individuals hospitalized | pH | <0.001 | 0.001 | <0.001 | <0.001 | |
| 50% treated | Secondary attack rate | θ | 0.881 | 0.881 | 0.877 | 0.872 |
| Antiviral treatment efficacy | εT | 0.101 | 0.100 | 0.100 | 0.099 | |
| Vaccine efficacy | εV | 0.001 | 0.002 | 0.006 | 0.011 | |
| Contact rate | c | 0.001 | 0.001 | 0.001 | 0.001 | |
| 1/(Duration of infectious period) | δ | <0.001 | 0.001 | <0.001 | <0.001 | |
| Proportion of infected individuals hospitalized | pH | <0.001 | 0.001 | <0.001 | <0.001 |