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Release curve-fitting equations of rapamycin-containing liposomes.
| Model | Fitting equation | Correlation coefficient r |
|---|---|---|
| Zero-order release model | Q = 0.0152 t + 0.4544 | 0.9101 |
| First-order release model | ln(1-Q) = −0.046 t − 0.5090 | 0.9770 |
| Higuchi model | Q = 0.1166 t1/2 + 0.2697 | 0.9673 |
| Ritger-Peppas model | lnQ = 0.2965 lnt − 0.1067 | 0.9600 |
| Weibull model | ln(1/1-Q) = 0.5311 lnt − 0.1704 | 0.9710 |
Q, accumulative release rate; t, time.
