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Urocortin and urocortin with triciribine reduced the oversecretion of (A) TGF-β1 and (B) CTGF in the plasma of diabetic rats. However, astressin reversed the effect of urocortin. *P<0.05 and **P<0.01, vs. control; #P<0.01 and ΔP<0.05, vs. DM and UCN + AST groups; $P>0.05, vs. DM group; ○P<0.05, vs. UCN group. TGF, transforming growth factor; CTGF, connective tissue growth factor; DM, diabetes mellitus; UCN, urocortin; AST, astressin.
