FIGURE 4.

Multitissue transcriptomic analysis of the AMI-induced functional signature. A, VennPlex analysis of AMI-regulated transcripts across the cortex, hippocampus, and striatum. B, core transcripts coherently regulated by AMI in at least two out of three experimental tissues. C, VennPlex analysis of AMI-regulated MSigDB signaling pathways across the cortex, hippocampus, and striatum. D, core signaling pathways coherently regulated by AMI in at least two out of three experimental tissues. E, collective Textrous! hierarchical word cloud created from the AMI signature transcript dataset (from B). F, individual Textrous! heatmap processing generated with the AMI signature transcript dataset (from B).