TABLE 2.
Phospholipid found in exosomes
Phospholipid classes detected are PE, PS, PI, PC, and the gangliosides GM2 and GM3. Fatty acid composition was determined from MS2 in which relative intensity is calculated within each lipid class, and where 100% represents the most abundant species found; ppm denotes the deviation of the experimental value from the theoretical.
| Class | Fatty acid | Lipid m/z/ppm | Relative intensity |
|---|---|---|---|
| % | |||
| PE | 18:1–16:0 | 716.5252/2.3 | 35 |
| PE | 18:1–18:1 | 742.5403/1.4 | 100 |
| PE | 18:1–18:0 | 744.556/1.5 | 42 |
| PE | 18:1–20:4 | 764.525/1.9 | 31 |
| PE | 18:0–20:4 | 766.5408/2.1 | 71 |
| PE | 18:0–20:3 | 768.5562/1.7 | 51 |
| PS | 16:0–18:1 | 760.5142/1.0 | 32 |
| PS | 18:1–18:1 | 786.53/1.2 | 24 |
| PS | 18:1–18:0 | 788.5454/0.9 | 100 |
| PS | 18:0–20:4 | 810.5278/−1.5 | 21 |
| PS | 18:1–22:0 | 844.6096/2.7 | 67 |
| PI | 18:1–18:1 | 861.5509/1.2 | 71 |
| PI | 18:0:18:1 | 863.5665/1.2 | 100 |
| PI | 18:0–20:4 | 885.5516/2.0 | 36 |
| PI | 18:0–20:3 | 887.5667/1.4 | 93 |
| PI | 18:0–20:2 | 889.582/1.0 | 57 |
| PC | 16:0–16:2 | 788.5456/1.1 | 50 |
| PC | 16:0–16:1 | 790.5606/0.3 | 21 |
| PC | 16:0–16:0 | 792.5767/0.9 | 20 |
| PC | 16:0–18:1 | 818.5914/−0.3 | 100 |
| PC | 18:1–18:0 | 846.6242/1.5 | 50 |
| GM3 | 16:0 | 1151.7080/1.9 | 52 |
| GM3 | 20:0 | 1207.7705/1.7 | 7 |
| GM3 | 22:0 | 1235.8017/1.5 | 9 |
| GM3 | 24:1 | 1261.8172/1.4 | 12 |
| GM3 | 24:0 | 1263.8325/1.1 | 16 |
| GM2 | 16:0 | 1354.7880/2.0 | 100 |
| GM2 | 18:0 | 1382.8184/1.3 | 8 |
| GM2 | 20:0 | 1410.8500/1.5 | 12 |
| GM2 | 22:0 | 1438.8826/2.4 | 21 |
| GM2 | 24:1 | 1464.8972/2.1 | 31 |
| GM2 | 24:0 | 1466.9118/0.9 | 34 |