Table 2.

Influences of factors on the levels of rMSC proliferation and osteogenic differentiation

	Adsorption vs coprecipitation of OGP	Dually loaded OGP and FN vs single loaded OGP or FN	Adsorption vs coprecipitation of OGP with adsorbed FN
Proliferation	−	+	−
ALP activity	−	+(aOF)/−(cO/aF)	+
OC secretion	+	+	+
Calcium deposition	+	+	+

Notes: +, significant increase; −, no significant difference.

Abbreviations: ALP, alkaline phosphatase; OC, osteocalcin; cO/aF, mineralization, coprecipitation of mineral and OGP, FN adsorption; aOF, mineralization, OGP and FN adsorption; OGP, osteogenic growth peptide; FN, fibronectin; rMSC, rat mesenchymal stem cell.