Table S3.
Characteristics of symptomatic patients in the coronary CTA cohort and patients in the randomly selected sample from the Western Denmark Cardiac Computed Tomography Registry, 2008–2012
| Coronary CTA cohort overall (n=18,899) |
Random samplea (n=250) |
|
|---|---|---|
| Male sex | 10,169 (53.8) | 107 (42.8) |
| Age, yearsb | 58 (50–66) | 56.5 (48–63) |
| Family history of premature CAD | 7,353 (38.9) | 97 (38.8) |
| Current lipid-lowering therapy | 5,883 (31.1) | 79 (31.6) |
| Current medical treatment for hypertension | 6,532 (34.6) | 84 (33.6) |
| Smoking status (current or former) | 9,504 (50.3) | 131 (52.4) |
| Diabetes | 1,035 (5.5) | 33 (13.2) |
| Previous PCI | 166 (0.9) | 0 |
| Previous cardiac surgery | 156 (0.8) | 1 (0.4) |
| Previous myocardial infarction | 193 (1.0) | 0 |
| Height (cm)b | 171 (165–178) | 171 (158–184) |
| Weight (kg)b | 78 (67–88) | 78 (56–100) |
| Creatinine level, μmol/Lb | 73 (63–83) | 72 (55–89) |
| Systolic blood pressure, mmHgb | 140 (126–151) | 138 (112–164) |
| Diastolic blood pressure, mmHgb | 81 (75–90) | 80 (65–95) |
| Left ventricular ejection fractionb | 60 (60–60) | 60 (60–60) |
| Angina type (if any) | ||
| Typical angina | 1,764 (9.4) | 22 (8.8) |
| Atypical angina | 5,844 (30.9) | 78 (31.2) |
| Unspecific chest pain | 4,760 (25.2) | 58 (23.2) |
| Dyspnea | 916 (4.8) | 8 (3.2) |
| Unknown | 5,615 (29.7) | 84 (33.6) |
| Priority | ||
| Acute | 78 (0.4) | 2 (0.8) |
| Subacute | 755 (4.0) | 2 (0.8) |
| Elective | 17,209 (91.1) | 230 (92.0) |
| Unknown | 857 (4.5) | 16 (6.4) |
| Kilo-electron voltb | 100 (100–120) | 120 (100–120) |
| Radiation dose | –c | –c |
| Iodine concentration, mg/mLb | 350 (350–370) | 370 (350–370) |
| Contrast volume, mLb | 80 (70–90) | 77.5 (70–90) |
| Preprocedural beta-blocker | 11,991 (63.4) | 164 (65.6) |
| Heart rhythm | ||
| Sinus rhythm | 17,794 (94.2) | 229 (91.6) |
| Atrial fibrillation | 108 (0.6) | 2 (0.8) |
| Other | 85 (0.4) | 2 (0.8) |
| Unknown | 912 (4.8) | 17 (6.8) |
| Heart rate (bpm)b | 59 (54–64) | 60 (55–65) |
| Cardiac CT quality | ||
| Good | 14,304 (75.7) | 184 (73.6) |
| Moderate | 1,897 (10.0) | 20 (8.0) |
| Nonevaluable | 828 (4.4) | 18 (7.2) |
| Unknown | 1,870 (9.9) | 28 (11.2) |
| CACS (Agatston) resultb | 0 (0–90) | 0 (0–75) |
| Coronary CTA result | ||
| Normal | 12,550 (66.4) | 164 (65.6) |
| Nonobstructive CAD | 2,213 (11.7) | 39 (15.6) |
| 1-vessel obstructive CAD | 2,012 (10.6) | 19 (7.6) |
| 2-vessel obstructive CAD | 673 (3.6) | 7 (2.8) |
| 3-vessel/LM obstructive CAD | 312 (1.7) | 6 (2.4) |
| Only CACS performed | 427 (2.3) | 6 (2.4) |
| Unknown | 712 (3.7) | 9 (3.6) |
| Consequence of coronary CTA results | ||
| Nothing further | 8,673 (45.9) | 96 (38.4) |
| Medical treatment | 3,313 (17.5) | 39 (15.6) |
| Referral to invasive coronary angiography | 3,216 (17.0) | 42 (16.8) |
| Referral to myocardial perfusion imaging | 632 (3.3) | 10 (4.0) |
| CACS is too high – referral to further testing | 157 (0.8) | 1 (0.4) |
| Referral to other noninvasive diagnostic testing | 399 (2.1) | 9 (3.6) |
| Unknown | 2,509 (13.4) | 53 (21.2) |
Notes:
a
250 randomly selected symptomatic patients who underwent coronary CTA at three university cardiac centers (Aarhus, Aalborg, and Odense) and two nonuniversity cardiac centers (Lillebaelt Hospital-Vejle and Hospital of Southwestern Denmark-Esbjerg);
b
values in median ± interquartile range;
c
was not estimated due to differences in registered dose units.
Abbreviations: CACS, coronary artery calcium scoring; CAD, coronary artery disease; CT, computed tomography; CTA, computed tomography angiography; LM, left main; PCI, percutaneous coronary intervention.