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. 2015 Jan 16;22(1):33–40. doi: 10.1097/LBR.0000000000000126

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Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivitives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.

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In vivo alveolar pCLE imaging at 488 nm in PAP patients revealed: (A) floating intra-alveolar complexes with high homogenous fluorescence (black arrows) against the background of the preserved alveolar elastin fibers (black arrowheads) and vessels (white arrowheads); (B) alveolar macrophages (arrows) separate or sticking together (some of them are giant); (C) moderately fluorescent fluid in the alveolar lumen (elastin fibers are shown with arrows); (D) normal alveoli with single alveolar macrophages (arrows). PAP indicates pulmonary alveolar proteinosis; pCLE, probe-based confocal laser endoscopy.