Fig 6. Survival of mice following 1 or 2 treatments with ascorbic acid (3 g/kg) after WBI.

After receiving 7.5 Gy WBI, mice were treated with 2 courses of ascorbic acid (1.5 g/kg × 2, immediately and 24 h after radiation, 3 g/kg in total), or a single administration (3 g/kg, immediately after radiation), or without administration, and their survival was monitored (A). Plasma levels of free radical metabolites were also measured 7 and 14 days after WBI (B). N = 15 in each group.