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Descriptive statistics of pharmacokinetic parameters for Sandoz MPH OCR and Concerta® in the fed study.
| Parameter (units) All mean ± SD | 54-mg fed (n = 21) |
|
|---|---|---|
| Sandoz MPH OCR | Concerta® | |
| AUC0–t (ng.h/mL) | 141.02 ± 43.11 | 148.57 ± 47.73 |
| AUC0–inf (ng.h/mL) | 148.92 ± 47.46 | 154.38 ± 51.61 |
| Cmax (ng/mL) | 12.55 ± 3.36 | 13.35 ± 4.04 |
| Tmax (h) | 5.17 ± 0.64 | 8.19 ± 2.64 |
| Kel (h−1) | 0.1599 ± 0.0341 | 0.1859 ± 0.0248 |
| T½ el (h) | 4.52 ± 0.92 | 3.79 ± 0.52 |
