Table 1. Degree of nerve injury and anticipated recovery.
Degree of nerve injury | Definition of nerve injury | Prognosis | Tinel sign | Surgical intervention |
---|---|---|---|---|
First (Neurapraxia) | Segmental demyelination Axonal continuity maintained; endoneurium, perineurium and epineurium, intact |
Favorable | None | None, distal decompression |
Second (Axonotmesis) | Discontinuity of axon and myelin; endoneurium, perineurium, and epineurium intact |
Favorable | Present, progressive | None, distal decompression, supercharge procedure |
Third | Discontinuity of axon, myelin and endoneurium; perineurium and epineurium intact | Favorable | Present, progressive | None, distal decompression, supercharge procedure |
Fourth | Only the epineurium remains intact | Unfavorable | Present; no progression | Nerve repair, graft, transfer |
Fifth (Neurotmesis) | Complete nerve transection | Unfavorable | Present; no progression | Nerve repair, graft, transfer |
Sixth | Mixed injury pattern | Variable | Variable | All options may be appropriate |