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. 2015 Feb;29(1):40–47. doi: 10.1055/s-0035-1544169

Table 1. Degree of nerve injury and anticipated recovery.

Degree of nerve injury Definition of nerve injury Prognosis Tinel sign Surgical intervention
First (Neurapraxia) Segmental demyelination
Axonal continuity maintained;
endoneurium, perineurium and epineurium, intact
Favorable None None, distal decompression
Second (Axonotmesis) Discontinuity of axon and myelin;
endoneurium, perineurium, and epineurium intact
Favorable Present, progressive None, distal decompression, supercharge procedure
Third Discontinuity of axon, myelin and endoneurium; perineurium and epineurium intact Favorable Present, progressive None, distal decompression, supercharge procedure
Fourth Only the epineurium remains intact Unfavorable Present; no progression Nerve repair, graft, transfer
Fifth (Neurotmesis) Complete nerve transection Unfavorable Present; no progression Nerve repair, graft, transfer
Sixth Mixed injury pattern Variable Variable All options may be appropriate