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. Author manuscript; available in PMC: 2015 Feb 4.
Published in final edited form as: Nat Rev Genet. 2008 Oct;9(10):776–788. doi: 10.1038/nrg2432

Table 2.

Current licensed DNA therapies

Vaccine target Product name Company involved Date licensed
and country
Target
organisms
Benefits
West Nile virus West Nile
Innovator
Centers for Disease Control
and Prevention and Fort Dodge
Laboratories
2005 USA Horses Protects against West Nile virus infection
Infectious
haematopoietic
necrosis virus
Apex-IHN Novartis 2005 Canada Salmon Improves animal welfare, increase food
quality and quantity
Growth hormone
releasing
hormone
LifeTide-SW5 VGX Animal Health 2007 Australia Swine
and food
animals*
Increases the number of piglets weaned
in breeding sows; significantly decreases
perinatal mortality and morbidity
Melanoma Canine
Melanoma
Vaccine
Merial, Memorial Sloan–Kettering
Cancer Center and The Animal
Medical Center of New York
2007 USA,
conditional
license
Dogs Treats aggressive forms of cancer of the
mouth, nail bed, foot pad or other areas as
an alternative to radiation and surgery
*

Refers to agricultural animals as opposed to pet animals — a higher level of stringency is required for approval for animals that are part of the food chain.