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ELISpot responses to each vaccine antigen present at all doses. (A) Overall background-subtracted cellular immune responses against four vaccine antigens. (B to E) Background-subtracted antigen-specific cellular immune responses in the 0.3, 1.0, and 3.0 mg groups to (B) HPV16 E6, (C) HPV16 E7, (D) HPV18 E6, and (E) HPV18 E7.
