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. 2015 Feb 15;6(1):54–66. doi: 10.4239/wjd.v6.i1.54

Figure 1.

Figure 1

Diagram of pathogenesis of diabetic cerebral vascular disease complication. NO: Endothelium-derived nitric oxide; ET-1: Endothelin-1; VCAM: Vascular cell adhesion molecule; ICAM: Intercellular adhesion molecule; TNF: Tumor necrosis factor; IL: Interleukin; NF-κB: Nuclear factor-κB; COX-2: Cyclooxygenase-2; PGI2: Prostacyclin: PAI-1: Prothrombus genes; TGF-β: Transforming growth factor beta; MCP-1: Monocyte chemoattractant protein-1; TF: Tissue factor; Ox-LDL: Oxidized low-density lipoproteins; FFAs: Free fatty acids.