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. 2015 Feb 15;6(1):67–79. doi: 10.4239/wjd.v6.i1.67

Table 4.

Odds ratio of susceptibility genes for autoimmune endocrinopathies[117,144-160]

T1D HT GD AD
HLA-DR3 3.5 3.7 2-4 5
MICA 1.6 2.5 2 7
PTPN22 1.8 1.6 1.6 1.5
CTLA-4 1.5 5 1.5 1.8

AD: Addison’s disease; CTLA-4: Cytotoxic T lymphocyte antigen 4; GD: Graves’ disease; HLA: Human leukocyte antigen; HT: Hashimoto’s thyroiditis; MICA: MHC class I polypeptide-related sequence A; PTPN22: Protein tyrosine phosphatase non-receptor type 22; T1D: Type 1 diabetes.