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Selectivity of vasopressin (AVP) V1a, AVP V1b and oxytocin (OT) receptors to AVP and OT.
| AVP | OT | |||||
|---|---|---|---|---|---|---|
| Receptor | V1a | V1b | OT | V1a | V1b | OT |
| Humans | 1.1 | 0.7 | 1.7 | 120 | >1000 | 0.8* |
| Rats | 2.6 | 0.3 | 1.7 | 71 | 294 | 1.0 |
| Mice | 1.3 | 0.3 | 1.8 | 46.1 | 94 | 0.6 |
Affinity values in Ki (nm);
defined as selective as compared with the two other receptors of that species by the selectivity criteria of having a two orders of magnitude lower Ki; References:
