Table 3.
P-value | Hazard Ratio | 95% CI | |
---|---|---|---|
Methylation Markers | |||
Any positive (EDNRB/DCC/p16) | 0.77 | 1.35 | [0.17, 10.5] |
Other risk factors | |||
Gender (Male vs. Female) | 0.88 | 0.9 | [0.24, 3.33] |
Smoking status – continuous for at least 1 year (Yes vs. No) | 0.19 | 2.79 | [0.61, 12.75] |
Overall Stage | 0.38 | ||
1 | 0 | - | |
2 | reference | [0.32, 6.86] | |
3 | 0.53 | [0.05, 5.85] | |
4 | 0.67 | [0.15, 3.13] | |
HPV (positive vs. negative) | 0.34 | 0.56 | [0.17, 1.86] |
Primary site | 0.005 | ||
Oral cavity | reference | ||
Oropharynx | 0.11 | [0.02, 0.50] | |
Larynx | 0.36 | [0.08, 1.71] | |
Unknown primary | 0 | - | |
T-classification | 0.12 | ||
1 | reference | ||
2 | 2.9 | [0.53, 15.86] | |
3 | 1.99 | [0.28, 14.12] | |
4 | 6.63 | [1.21, 36.37] | |
Tx | 0 | - | |
N-classification | 0.31 | ||
0 | reference | ||
1 | 4.07 | [0.57, 28.95] | |
2A | 0 | - | |
2B | 2.67 | [0.55, 12.87] | |
2C | 1.51 | [0.14, 16.68] |