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. Author manuscript; available in PMC: 2016 Jan 3.
Published in final edited form as: Head Neck. 2015 Jun 26;38(1):9–14. doi: 10.1002/hed.23842

Table 3.

Univariate analysis for local recurrence-free survival.

P-value Hazard Ratio 95% CI
Methylation Markers
Any positive (EDNRB/DCC/p16) 0.77 1.35 [0.17, 10.5]
Other risk factors
Gender (Male vs. Female) 0.88 0.9 [0.24, 3.33]
Smoking status – continuous for at least 1 year (Yes vs. No) 0.19 2.79 [0.61, 12.75]
Overall Stage 0.38
  1 0 -
  2 reference [0.32, 6.86]
  3 0.53 [0.05, 5.85]
  4 0.67 [0.15, 3.13]
HPV (positive vs. negative) 0.34 0.56 [0.17, 1.86]
Primary site 0.005
  Oral cavity reference
  Oropharynx 0.11 [0.02, 0.50]
  Larynx 0.36 [0.08, 1.71]
  Unknown primary 0 -
T-classification 0.12
  1 reference
  2 2.9 [0.53, 15.86]
  3 1.99 [0.28, 14.12]
  4 6.63 [1.21, 36.37]
  Tx 0 -
N-classification 0.31
  0 reference
  1 4.07 [0.57, 28.95]
  2A 0 -
  2B 2.67 [0.55, 12.87]
  2C 1.51 [0.14, 16.68]