Table 2.
In vivo pseudodiffusion calculations for the ROI-based and voxelwise methods in normal volunteers
Low b=(0,50) | Low b=(0,10,25,50) | |||
---|---|---|---|---|
ROI | Dp | 37.0 (9.7) | 85.9 (25.1) | P < 0.001 |
CV | 0.26 | 0.28 | ||
Voxelwise | Mean Dp | 25.2 (6.0) | 61.3 (18.3) | P < 0.001 |
CV | 0.11 | 0.10 | ||
Median Dp | 19.0 (6.6) | 35.0 (13.3) | P < 0.001 | |
CV | 0.25 | 0.18 | ||
% Outliers | 31.3 (7.9) | 10.1 (5.5) | P < 0.001 |
The units of the b-values are s/mm2. The units of the pseudodiffusion values are μm2/ms. Each set of low b-values was in addition to b=(100,150,200,400,800) s/mm2. Standard deviations are shown in parentheses. P-values are the result of a paired two-sample t-test.
Abbreviations: Dp = pseudodiffusion, CV = coefficient of variation.