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Criteria for scoring biological responses in periprosthetic tissues of L-TDRs
| Score | Necrosis | Hemosiderin | Innate inflammation (macrophages) | Vascularization | ||
|---|---|---|---|---|---|---|
| Tissue percent area | Tissue percent area | Number of cells | Tissue percent area | Number of blood vessels | Tissue percent area | |
| 0+ | 0 | 0 | 0 | 0 | 0 | 0 |
| 1+ | Scattered or Isolated | < 10 | 1–9 | < 10 | < 10 | < 10 |
| 2+ | < 25 | 10–50 | 10–50 | 10–50 | 10–50 | 10–25 |
| 3+ | > 25 | > 50 | > 50 | > 50 | > 50 | > 25 |
L-TDRs = lumbar total disc replacements.
