Table 3.
Survival and failures after reconstructions with megaprostheses: data from previous reports
| Author | Year | Number of cases | Average followup (months; range) | Anatomical site | Prosthesis type | Cement | Survival at 5 years | Survival at 10 years | Infection failure | Prosthesis breakage | Loosening failure |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Ahlmann et al. [1] | 2006 | 211 | 37.3 (1–204) | Lower limb | MSRS™ (Stryker, Mahwah, NJ, USA) | Cemented | 78% | 60% | 5.2% | 4.3% | 2.4% |
| Gosheger et al. [16] | 2006 | 250 | 45 | Mixed | MUTARS® (Implantcast,Buxtehude, Germany) | Uncemented | 89.7% upper limb, 68.5% lower limb | 60.4 % overall | 12% | 1.6% | 8% |
| Biau et al. [4] | 2006 | 91 | 62 (0.5–343) | Distal femur, proximal tibia | GUEPAR® (Paris, France) | Cemented | 85% femur, 72% tibia | 55% femur,43% tibia | 11.0% | 7.7% | 15.4% |
| Myers et al. [29] | 2007 | 335 | 144 (60–360) | Distal femur | STANMORE (Stanmore, UK) | Mixed | 83% | 67% | 9.6% | 2% | – |
| Jeys et al. [25] | 2008 | 661 | 60 (120–420) | Mixed | STANMORE | Cemented | – | 58% | 11.3% | 6.1% | 11.3% |
| Guo et al. [19] | 2008 | 104 | 47 (12–118) | Distal femur, proximal tibia | Custom-made | Cemented | 70.5% | – | 6.7% | 6.7% | 2.9% |
| Shehadeh et al. [34] | 2010 | 232 | 120 (60–324) | Mixed | MSRS™ (Stryker) | Cemented | 84% | 72% | 10.8% | 4.3% | 7.4% |
| Schwartz et al. [33] | 2010 | 186 | 96 (1–336) | Distal femur | Modular r-h custom-made (Stryker/Howmedica, Mahwah, NJ, USA; Techmedica, Camarillo, CA, USA; Dow-Corning Wright, Arlington, TN, USA) | Cemented | 88% | 77% (20-year 58%) | 3.2% | 5.4% | 11.8% |
| Healey et al. [21] | 2013 | 82 | 43 (6–131) | Distal femur | COMPRESS® (Biomet, Warsaw, IN, USA) | Uncemented | 85% | 80% | 6.1% | 6.1% | 3.7% |
| Pala et al. [31] | 2013 | 295 | 50 (24–96) | Mixed | GMRS™ (Stryker) | Uncemented | 68% | 58% | 9.5% | 0% | 5.1% |
| Our series | 2013 | 200 | 67 (24–149) | Lower limb | Megasystem C® (Waldemar Link, Hamburg, Germany) | Mixed | 75.9% | 66.2% | 9.5% | 8% whole series 0.8% of 116 patients with modified cone | 3.0% |