Fig. 3.

Differential dose-response cytotoxicity to human MSCs with four commonly used corticosteroids is shown in the graph. Mean optical density of the MTS tetrazolium dye-based cell viability assay measured the survival of human MSCs 24 hours after a 60-minute treatment with 1× PBS solution (control), or one of the following corticosteroids: dexamethasone (4 mg/mL), triamcinolone (40 mg/mL), methylprednisolone (40 mg/mL), or betamethasone (6 mg/mL). The corticosteroids were applied in a scaled titration including 3.125%, 6.25%, 12.5%, 25%, 50%, 75%, or 100% of the concentration in the commercially available preparations. *Table 3 shows specific pairwise comparisons.