Capsid assembly and budding from a domain. Two-dimensional slices of configurations at different times extracted from MD simulations for ead = 0.4α, rdomain = 35σ, and εDM/ε0 = 0.875 (γ ≈ 1.3 kBT/σ). The membrane wraps the growing capsid (A–D) until the complete, enveloped capsid is connected to the rest of the membrane by a narrow neck (E). Finally, thermal fluctuations lead to fusion of the neck and the encapsulated capsid escapes from the membrane (F). To see this figure in color, go online.